Third Generation Polynucleotides Skin Boosters

Nucleofill, Crystal PDRN, and Rejuran Healer

Skin health and appearance are one of the most important aspects of your face. Looking after your skin to keep it young and fresh is what we specialise in here at Aestha clinic. Our team of advanced medical aesthetics experts is always on the lookout for the latest innovations and best products available in the global beauty and aesthetic medicine market. In this feature, we will present and discuss one of the latest trends in regenerative medicine skin care.

3^rd generation polynucleotides skin boosters work at the cellular level to boost skin’s rejuvenation, cleansing effects of free radicals, and metabolic scavengers. Improved circulation and oxygenation are also important benefits of this type of treatment.

The unique features of polynucleotides skin boosters

These are skin boosters that contain high molecular weight polynucleotide chains or PN.

A polynucleotide is a chain of more than 10 nucleotides that are in every cell’s DNA, when they are linked together they are called PolyNucloetide. True PN solution is very liquidy almost like a serum and better administered as nano injections or via microneedling therapy.

PDRN products is a less concentrated version of polynucleotides and has additional hyaluronic acid and niacinamide to help skin hydration, reduce sensitivities and improve skin circulation.

The strong moisturizing effect is due to a combination of hyaluronic acid and polynucleotides as they have strong water retention capabilities at the molecular level. It is almost as “electrostatic sponge” attracting water, and improving cellular wellbeing by connecting water molecules and improving nutrients and oxygen exchange within the cells.

It is an excellent ability to improve cellular energy mechanisms, ensures that the cell gets rid of metabolic waste, and blocks free radicals to connect to DNA chains.

The difference between products :

Concentration of PN
Additional ingredients such as hyaluronic acid and vitamins
PN or PDRN
The amount available for treatment
The delivery ie technique of administration

The product and type of polynucleotides skin boosters should be selected on an individual basis after a consultation with an Aestha clinic practitioner. A higher concentration is not always the best option. A higher concentration of PN is better for under eye area, versus PDRN is often better for a whole face skin improvement, especially when ageing signs are present.

Indications:

Skin’s laxity and ageing with poor circulation
Dehydrated, rough and inflamed skin
Sun damaged and subjected to oxidative stress (ie smoking and other unhealthy lifestyle choices such as high sugar intake) skin
Dark circles under eyes and post inflammatory pigmentation
Scars at any stage
Skin hydration
Lifting effect
Bio-stimulation of elastin and collagen
Active Acne treatment
Acne scarring improvement
Hair growth stimulation

Crystal PDRN

This product is a combination of the most effective ingredients for revitalisation- polynucleotides (PDRN), niacinamide, and hyaluronic acid. Crystal PDRN stimulates the formation of tissue and cell division while helping improve the overall appearance of the skin within a period of time.

EFFECTS

Promotes cell regeneration
Renews radiance and smoothness of skin tone
Improves skin elasticity
Balances inner skin layer
Replenishes moisture
Provides anti-aging effect
Improves micro wrinkles
Creates a clean and clear complexion for patients by increasing moisture within the skin

An initial course of 3 treatments is required, 3-4 weeks apart for optimal results. After the intensive course, a repeat treatment is advised every 4-6 months to further maintain and enhance skin quality.

SIDE EFFECTS

Needle marks
Possible bruising
Skin sensitivity

No significant other side effects have been reported. Adverse effects of this product are extremely rare.

Nucleofill

Nucleofill is a product based on active polynucleotides specially designed for skin renewal and bio-restructuring. This product is not intended for adding volume. The natural polynucleotide-based bio-stimulating gels, with high viscosity, are designed to protect and rejuvenate the skin. It is compatible with a mesotherapy protocol.

EFFECTS

Provides a visible rejuvenating effect without affecting facial features
Reduces the appearance of wrinkles and creases and firms the skin
Improves skin texture of skin exposed to oxidative stress (due to air pollution, sun exposure, smoking, poor diet)
Replenishes dehydrated skin
Extends the efficacy and effects of other aesthetic products. It is used to prepare the skin before injections.
Has a lifting effect

It’s recommended to have 2 treatments with 2-4 weeks in between each session, in severe cases you can have up to 4 treatments within 2-4 weeks intervals.

SIDE EFFECTS

Bruising may occur
Some swelling in the injection area 1-2 days

No other side effects have been reported.

Rejuran Healer

Rejuran Healer (PN) is a treatment designed for skin healing and rejuvenation. It contains highly bio-compatible DNA fragments (polynucleotides), to improve the overall condition of damaged/ageing skin. Rejuran Healer is indispensable in the treatment of acne, as well as in post-acne procedures aimed at restoring the skin and giving it a smooth and healthy tone.

EFFECTS

Recovers damaged cells and stimulates repair processes
Improves the elasticity of the skin
Restores microcirculation in tissue
Reduces the process of inflammatory manifestation of acne
Promotes narrowing of pores
Accelerates healing and scarring of the skin
Increases the metabolic activity of cells, preventing the formation of new wrinkles

It is recommended to have 4 sessions at 3-4 week intervals. Results may take up to a month post the last treatment depending on the genetic and environmental factors of each individual.

SIDE EFFECTS: