Maxillofacial practitioner and official international Jalupro trainer Dr. Tetiana Teslya answers four of the questions she hears most often about Jalupro and Profhilo, two injectable treatments used to improve skin quality but with very different formulations.

Q1. Jalupro and Profhilo are both described as skin boosters. Are they actually doing the same thing?

Not exactly. Profhilo is based on high- and low-molecular-weight hyaluronic acid and is designed to improve hydration, elasticity and skin laxity without behaving like a traditional volumising filler.1

Jalupro is different because it is a range rather than one single product. When patients compare it with Profhilo, I am usually talking about Jalupro Super Hydro. It contains high- and low-molecular-weight hyaluronic acid together with seven amino acids and three peptides.2

So while both can improve skin quality, Profhilo is primarily an HA-based bioremodelling treatment, whereas Jalupro Super Hydro combines hydration with amino acids and peptides that support collagen production and connective tissue.

Q2. When would you choose Jalupro, and when would you choose Profhilo?

If the main concern is dehydration, reduced elasticity or early skin laxity, Profhilo can be a very good option. Clinical studies have reported improvements in hydration, elasticity, density and skin laxity following treatment.1,3

I tend to choose Jalupro when I want to go beyond hydration and include stronger support for collagen and connective tissue. Jalupro Super Hydro has been studied for its effects on both the dermis and the retinacular cutis, which is part of the connective tissue that helps support the face.2

The decision really depends on what I see during assessment. Some patients mainly need hydration and elasticity; others need a treatment plan that also addresses collagen support and deeper tissue quality.

Q3. How many sessions are usually needed, and when do results start to appear?

Profhilo is commonly performed as two sessions around four weeks apart. Patients often notice improved hydration first, followed by more gradual changes in texture, elasticity and firmness over the following weeks.1,3

With Jalupro, the protocol depends on the formulation being used. Jalupro Super Hydro has been studied in treatment courses spaced approximately four weeks apart, and I tailor the number of sessions according to the skin quality, age and treatment area.2

Neither treatment is intended to give the immediate volumising effect of a filler. The change develops more gradually, which is why they are popular with patients who want the skin to look fresher and more supported without changing their facial features.

Q4. If someone simply says, “I want better skin”, how do you decide which one they need?

I first look at what “better skin” actually means for that person. Their main concern may be dehydration, fine lines, reduced elasticity, thinning skin or early laxity, and each of those can lead me towards a different treatment plan.

If hydration and skin remodelling are the priority, Profhilo may be enough. If I also want amino acids and peptides to support collagen and deeper connective tissue, I am more likely to consider Jalupro Super Hydro.1,2

The important point is that these treatments are not interchangeable simply because they are both described as skin boosters. The right choice depends on the skin itself, the area being treated and what we are trying to achieve.