Weight loss

without compromising

skin and hair health

What is GLP-1 Microdosing?

GLP-1 microdosing represents a more nuanced approach to weight loss therapy, involving smaller, flexible doses—often through compounded versions of these medications—to minimise side effects while still achieving meaningful weight loss benefits. This innovative approach can significantly reduce Ozempic side effects, support a more tailored treatment plan, and provide a more affordable pathway to using these otherwise costly weight loss injections.

GLP-1 microdosing represents a more nuanced approach to weight loss therapy, involving smaller, flexible doses—often through compounded versions of these medications—to minimise side effects while still achieving meaningful weight loss benefits. This innovative approach can significantly reduce Ozempic side effects, support a more tailored treatment plan, and provide a more affordable pathway to using these otherwise costly weight loss injections.

Bioregenerative

Restoring Treatments

At Aestha Clinic, our expert medical professionals have recognised the unique challenges that come with GLP-1 therapy and have developed comprehensive GLP-1 microdosing protocols that go beyond simple weight management. Our approach focuses on protecting and enhancing skin and hair health as well as general wellbeing throughout the entire weight loss journey, addressing the aesthetic concerns that many patients experience but few clinics properly prepare for.

Find your treatment

Represent one of the cornerstones of our approach to GLP‑1 skin protection. We utilize two distinct formulations depending on patient needs: Jalupro Classic for younger GLP‑1 micro‑dosing patients focusing on prevention, and Jalupro Super Hydro for patients requiring enhanced hydration support. These treatments work by delivering essential amino acids and hyaluronic acid directly to the dermis, stimulating fibroblast activity for natural collagen production while preventing the early semaglutide skin changes that can develop even with careful dosing protocols.

Before After 1 Jalupro Super Hydro
Jalupro Super Hydro:

For patients requiring enhanced hydration

  • Advanced formulation with increased hyaluronic acid content
  • Targets severe dehydration from GLP‑1 therapy
  • Alternating monthly protocol with other treatments
Before After 3 Jalupro Classic
Jalupro Classic:

For younger patients focusing on prevention

  • Formulated with essential amino acids and hyaluronic acid
  • Stimulates fibroblast activity for natural collagen production
  • Monthly treatments for 3 sessions
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Represent perhaps our most advanced collagen stimulation technologyfor GLP-1 patients. This innovative treatment combines the immediate benefits of hyaluronicacid hydration with the long-term collagen stimulation provided by Poly D-Lactic Acid (PDLA).The dual-action formula provides immediate skin plumping that can address Ozempic faceconcerns while simultaneously triggering a collagen production cascade that continuesworking for up to 24 months.

Before After 1
Juvelook Hybrid Biostimulatio

Juvelook represents our most advancedcollagen stimulation technology.

  • Dual-action formula: CombinesHyaluronic Acid (HA) and Poly D-LacticAcid (PDLA)
  • Immediate hydration: HA providesinstant skin plumping
  • Long-term collagen stimulation: PDLAcontinues working for up to 24 months
  • Treatment schedule: 3 sessions over 3months for optimal results
Before After 1
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The science behind Julaine is particularly relevant for GLP-1 patients because it addressesboth the immediate hydration needs and the long-term structural support requirements thatarise during weight loss. The hyaluronic acid component provides instant volume andhydration, while the PDLA microspheres gradually stimulate the body's natural collagenproduction processes, creating lasting improvements in skin thickness, elasticity, and overallquality.

Before After 1
Julaine Advanced Skin Nutrition

Julaine therapy provides comprehensive skin nutrition through:

  • Multi-vitamin amino acid complex
  • Enhanced bioavailability formulation
  • Alternating monthly schedule with NCTF treatments
  • Targeted nutritional support for GLP-1- related deficiencies
Before After 1
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Our NCTF 135HA treatments deliver an impressive array of 55 active ingredients, includingessential vitamins A, C, E, K, and the complete B complex for metabolic support. Theformulation includes 23 essential and non-essential amino acids crucial for collagen synthesis,powerful antioxidants like glutathione and alpha-lipoic acid for cellular protection, and keyminerals including zinc, selenium, and magnesium for comprehensive skin repair. Thenucleotides included in the formulation support cellular repair and regeneration during thestress of weight loss.

Before After 1
NCTF 135HA Cellular Regeneration

NCTF 135HA delivers 55 active ingredients including:

  • Vitamins: A, C, E, K, B complex
  • Amino acids: 23 essential and non-essential
  • Antioxidants: Glutathione, alpha-lipoic acid
  • Minerals: Zinc, selenium, magnesium
  • Nucleotides: For cellular repair and regeneration
Before After 1
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For GLP-1 patients requiring significant volume restoration utilise poly-L-lactic acid microspheres to provide gradual, natural volume building that can dramaticallyimprove the appearance of Ozempic face. Unlike traditional dermal fillers that provideimmediate but temporary results, Sculptra works by stimulating the body's own collagenproduction processes, creating improvements that can last 2+ years. Our age-specificprotocols ensure that patients receive the optimal number of treatments customised for theirindividual GLP-1 microdosing journey and aesthetic goals.

Before After 1
Sculptra Deep Volume Restoration

For patients requiring significant volume restoration, Sculptra provides:

  • Poly-L-lactic acid microspheres for gradual, natural volume building
  • Long-lasting results: Effects continue for 2+ years
  • Age-specific protocols: 1-2 sessions/year for 30-45 age group, 2-3 sessions/year for over 45
  • Deep dermal action: Targets fundamental skin architecture
Before After 1
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The Fotona 4D laser protocols represent some of the most advanced non-invasive skintightening technology available today. Our standard Fotona 4D approach for 30-45 age groupGLP-1 patients utilises a four-dimensional treatment approach incorporating SMOOTH®,FRAC3®, PIANO®, and SupErficial™ modes. Each mode targets different layers and aspects of skin architecture, with treatments calibrated to achieve optimal collagen stimulation at targettemperatures of 42.5°C-43°C.

Before After 1
Standard Fotona 4D (30-45 age group):
  • Frequency: Every 6-8 weeks
  • Four-dimensional approach: SMOOTH®, FRAC3®, PIANO®, and SupErficial™ modes
  • Target temperature: 42.5°C-43°C for optimal collagen stimulation
  • Results: Immediate tightening with progressive improvement
Fotona 4D + Intraoral (Over 45 age group):
  • Enhanced protocol: Includes intraoral treatment for comprehensive lifting
  • SMOOTH™ Mode: Works from inside the mouth targeting underlying tissues
  • Frequency: Every 6-8 weeks for maximum efficacy
  • Comprehensive approach: Addresses both external and internal skin architecture
Book Now

For GLP-1 patients requiring significant volume restoration utilise poly-L-lactic acid microspheres to provide gradual, natural volume building that can dramaticallyimprove the appearance of Ozempic face. Unlike traditional dermal fillers that provideimmediate but temporary results, Sculptra works by stimulating the body's own collagenproduction processes, creating improvements that can last 2+ years. Our age-specificprotocols ensure that patients receive the optimal number of treatments customised for theirindividual GLP-1 microdosing journey and aesthetic goals.

Before After 1
Sculptra Deep Volume Restoration

For patients requiring significant volume restoration, Sculptra provides:

  • Poly-L-lactic acid microspheres for gradual, natural volume building
  • Long-lasting results: Effects continue for 2+ years
  • Age-specific protocols: 1-2 sessions/year for 30-45 age group, 2-3 sessions/year for over 45
  • Deep dermal action: Targets fundamental skin architecture
Before After 1
Book Now

Provides comprehensive skin nutrition through a sophisticated multi-vitaminamino acid complex designed specifically for enhanced bioavailability. For GLP-1 patients, thistreatment addresses the nutritional deficiencies that commonly develop due to reduced foodintake and altered absorption patterns. The targeted nutritional support helps prevent many ofthe skin and hair changes associated with Mounjaro and Wegovy side effects while supportingoverall metabolic health during weight loss.

Before After 1

The combination of Daigo metabiotics and GLP-1 weight loss treatment represents apotentially powerful synergistic approach to comprehensive health optimisation. Daigo’scontributions include direct delivery of beneficial bacterial metabolites, immune systemrebalancing, telomere protection, and cellular longevity enhancement. Meanwhile, GLP-1contributions encompass metabolic optimisation, gut transit modulation, appetite regulation,and inflammation reduction. This integrated approach addresses both the immediate needs for weight management andmetabolic health improvement whilst simultaneously supporting long-term cellular healthand longevity. The combination targets multiple pathways in the gut-brain-metabolic axis,creating a comprehensive intervention that exceeds what either treatment could achieveindependently.

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Our NCTF 135HA treatments deliver an impressive array of 55 active ingredients, includingessential vitamins A, C, E, K, and the complete B complex for metabolic support. Theformulation includes 23 essential and non-essential amino acids crucial for collagen synthesis,powerful antioxidants like glutathione and alpha-lipoic acid for cellular protection, and keyminerals including zinc, selenium, and magnesium for comprehensive skin repair. Thenucleotides included in the formulation support cellular repair and regeneration during thestress of weight loss.

Before After 1
NCTF 135HA Cellular Regeneration

NCTF 135HA delivers 55 active ingredients including:

  • Vitamins: A, C, E, K, B complex
  • Amino acids: 23 essential and non-essential
  • Antioxidants: Glutathione, alpha-lipoic acid
  • Minerals: Zinc, selenium, magnesium
  • Nucleotides: For cellular repair and regeneration
Before After 1
Book Now

The Fotona 4D laser protocols represent some of the most advanced non-invasive skintightening technology available today. Our standard Fotona 4D approach for 30-45 age groupGLP-1 patients utilises a four-dimensional treatment approach incorporating SMOOTH®,FRAC3®, PIANO®, and SupErficial™ modes. Each mode targets different layers and aspects of skin architecture, with treatments calibrated to achieve optimal collagen stimulation at targettemperatures of 42.5°C-43°C.

Before After 1
Standard Fotona 4D (30-45 age group):
  • Frequency: Every 6-8 weeks
  • Four-dimensional approach: SMOOTH®, FRAC3®, PIANO®, and SupErficial™ modes
  • Target temperature: 42.5°C-43°C for optimal collagen stimulation
  • Results: Immediate tightening with progressive improvement
Fotona 4D + Intraoral (Over 45 age group):
  • Enhanced protocol: Includes intraoral treatment for comprehensive lifting
  • SMOOTH™ Mode: Works from inside the mouth targeting underlying tissues
  • Frequency: Every 6-8 weeks for maximum efficacy
  • Comprehensive approach: Addresses both external and internal skin architecture
Book Now

The Fotona 4D laser protocols represent some of the most advanced non-invasive skintightening technology available today. Our standard Fotona 4D approach for 30-45 age groupGLP-1 patients utilises a four-dimensional treatment approach incorporating SMOOTH®,FRAC3®, PIANO®, and SupErficial™ modes. Each mode targets different layers and aspects of skin architecture, with treatments calibrated to achieve optimal collagen stimulation at targettemperatures of 42.5°C-43°C.

Before After 1
Standard Fotona 4D (30-45 age group):
  • Frequency: Every 6-8 weeks
  • Four-dimensional approach: SMOOTH®, FRAC3®, PIANO®, and SupErficial™ modes
  • Target temperature: 42.5°C-43°C for optimal collagen stimulation
  • Results: Immediate tightening with progressive improvement
Fotona 4D + Intraoral (Over 45 age group):
  • Enhanced protocol: Includes intraoral treatment for comprehensive lifting
  • SMOOTH™ Mode: Works from inside the mouth targeting underlying tissues
  • Frequency: Every 6-8 weeks for maximum efficacy
  • Comprehensive approach: Addresses both external and internal skin architecture
Book Now

Results

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All the knowledge you need,

in one e-book GLP-1 Microdosing

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FAQ’S

What is GLP-1 microdosing and how does it prevent Ozempic face?

GLP-1 microdosing involves taking smaller doses of semaglutide, tirzepatide, or other GLP-1 medications to reduce side effects while maintaining weight loss benefits. Combinedwith our aesthetic protocols, it helps prevent Ozempic face by supporting gradual weightloss and collagen protection. The slower rate of weight loss allows skin to adapt naturallywhile our treatments provide additional support for collagen production and volumemaintenance.

How quickly will I see results from GLP-1 aesthetic treatments?

Results vary by age group and treatment protocol. Patients under 30 typically see enhancedhydration within 1-4 weeks, while those aged 30-45 notice visible texture improvementwithin 4-8 weeks. Patients over 45 often experience significant skin firmness improvementwithin 8-12 weeks. The most dramatic improvements typically occur during the 3-6 monthtimeframe when collagen stimulation effects reach their peak.

Can I start aesthetic treatments while already on Ozempic or Mounjaro?

Absolutely! Our GLP-1 aesthetic protocols are specifically designed for patients already onsemaglutide, tirzepatide, or other GLP-1 medications. We’ll assess your current skincondition, duration of treatment, and rate of weight loss to customise a treatment plan thataddresses your specific needs and concerns.

What's the difference between Jalupro and Juvelook for GLP-1 patients?

Jalupro is an amino acid-based collagen stimulator that’s ideal for hydration and nutritionalsupport, particularly for younger patients or those requiring enhanced moisture restoration.Juvelook is a hybrid PDLA/HA formulation that provides both immediate hydration andlong-term collagen stimulation lasting up to 24 months, making it ideal for patients withmore significant volume loss or those requiring comprehensive skin architecture support.

How do IV treatments help with GLP-1 side effects?

Our specialised IV protocols provide targeted support for the unique challenges of GLP-1therapy. They deliver antioxidant support to combat oxidative stress from rapid weight loss,cellular regeneration support with NAD+ and glutathione, energy enhancement to combatGLP-1 fatigue, and skin brightening and collagen support with high-dose Vitamin C. Theintravenous delivery ensures maximum bioavailability, especially important for patients withaltered absorption patterns.

Are there any risks associated with combining GLP-1 microdosing and aesthetic treatments?

When performed by qualified medical professionals, the combination of GLP-1 microdosingand aesthetic treatments is very safe. Our protocols are specifically designed to supportand enhance the beneficial effects of GLP-1 therapy while minimising potential side effects.We conduct thorough medical evaluations and maintain careful monitoring throughouttreatment to ensure safety and optimise outcomes.

How long do the aesthetic benefits last after completing treatment?

The duration of benefits varies by treatment type and individual patient factors.Biostimulator treatments like Juvelookand Sculptra and Julaine can provide benefits lasting12-24 months, while Fotona laser effects typically last 6-12 months. IV therapy benefits aremore immediate and shorter-term, which is why we recommend ongoing maintenanceprotocols. Most patients find that periodic maintenance treatments can sustain theirimprovements indefinitely.

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Your Consultation Today

At our clinic, we understand that achieving natural-looking rejuvenation requires both advanced techniques and personalised treatment plans.

We take pride in offering this cutting-edge treatment as part of our commitment to providing effective, minimally invasive solutions that work with your body’s natural processes rather than against them.