a second-generation poly-L-lactic (PLLA) injectable
Julaine Biostimulator Treatment: The Perfect Candidate Guide
Julaine biostimulator represents the latest advancement in regenerative aesthetic medicine, offering patients natural, long-lasting skin rejuvenation through innovative PLLA (poly-L-lactic acid) technology. At Aestha Clinic, we specialise in regenerative treatments, and our doctors are trained in Julaine treatments. We are one of only 10 clinics authorised to offer this treatment in the UK.
What is Julaine Biostimulator?
Julaine is a next-generation collagen biostimulator designed to improve skin quality, density, and structure by triggering your body’s natural regenerative response. Unlike traditional dermal fillers that add instant volume, Julaine works subtly, encouraging your skin to rebuild itself from within using polylactic acid (PLLA) microspheres.
This biodegradable biostimulator promotes natural production of collagen and elastin in the skin, offering gradual transformation with results potentially lasting up to 2 years.

Ideal Candidates for Julaine Treatment
Age and Skin Profile
The ideal age to start Julaine biostimulator treatment is in the early 30s, though patients aged 30-65 with early to moderate signs of aging see optimal results. Perfect candidates typically experience:
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- Loss of skin firmness and elasticity
- Fine lines and mild wrinkles
- Decreased skin hydration and radiance
- Early facial volume loss, particularly mid-to-lower face
- Skin laxity without severe sagging
Patient Expectations and Commitment
Julaine isn’t about overnight transformation – this treatment is for patients who want to look fresher, firmer and better supported over time. Ideal candidates understand:
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- Results develop gradually over 2-6 months
- Treatment requires 3 sessions spaced 4-6 weeks apart
- Natural-looking enhancement rather than dramatic change
- Long-term skin health investment approach

Julaine Treatment Process and Results
The treatment plan comprises three sessions carried out 3-4 weeks apart, with visible results seen after the first treatment. Initial improvements become visible within 4-6 weeks, with maximum results appearing after 2-3 months and effects lasting up to 24 months.
Julaine is particularly effective for deep tissue filling and application at the dermal-subcutaneous junction, helping smooth lines and wrinkles while restoring facial volume naturally.
Complementary Treatments at Aestha Clinic
Medical-Grade Chemical Peels
A light to medium chemical peel performed 4-6 weeks before treatment can remove dead skin cells and prepare the treatment area, allowing better penetration and maximising collagen stimulation. Our chemical peels work synergistically with Julaine by:
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- Accelerating cellular turnover
- Improving skin texture and tone
- Creating optimal conditions for biostimulator effectiveness
Microneedling with PRP
Biostimulatory agents are often paired with microneedling and PRP to enhance collagen production, accelerate results, and improve skin health from multiple angles. This combination offers:
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- Enhanced collagen production through multiple pathways
- Improved treatment penetration
- Comprehensive skin texture improvement
- Accelerated healing and regeneration
Radiofrequency Skin Tightening
RF microneedling devices such as Secret Pro are best combined with biostimulator injectables. RF treatments provide immediate skin tightening while Julaine works on long-term collagen rebuilding.
IPL Photofacial Therapy
While Julaine addresses structural concerns through collagen stimulation, IPL targets:
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- Pigmentation irregularities
- Vascular concerns and redness
- Overall skin tone improvement
- Enhanced skin clarity and radiance
Strategic Injectable Combinations
In many cases, a combination approach delivers the best results: HA Fillers provide instant lift and smooth targeted lines, while biostimulators rebuild the skin’s internal scaffolding for progressive improvement.
Julaine Safety Profile and Contraindications
Julaine is CE-marked for safety and has undergone rigorous clinical testing, with side effects usually mild and temporary – including swelling, redness, or tenderness around injection sites.
Treatment is not suitable for:
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- Pregnancy or breastfeeding
- Active skin infections or inflammation
- Autoimmune disorders affecting healing
- Unrealistic expectations for immediate results
Julaine Safety Profile and Contraindications
Expert Assessment and Personalised Protocols
Collagen stimulation should be paced – applying high level stimulation at intervals when required, maintained with low-level biostimulation. Our comprehensive consultations evaluate skin condition, lifestyle factors, and aesthetic goals to create customised treatment plans.
Comprehensive Approach
We combine Julaine with complementary treatments, timing them strategically to enhance synergistic effects while minimising downtime. Our multi-modal approach addresses both symptoms and root causes of skin aging.
Long-term Results Focus
Clinical studies show that 75 percent of women preferred gradual results lasting two years over immediate results lasting 12 months. We focus on sustainable, natural-looking improvements that enhance your individual beauty.
Julaine provides long-term skin rejuvenation, addressing volume loss, fine lines, and skin laxity while improving hydration and overall skin health. This treatment represents a proactive approach to aging that works with your body’s natural processes.
Schedule Your Julaine Consultation
Ready to discover if the Julaine biostimulator treatment is right for you? At Aestha Clinic, our experienced practitioners will assess your skin, discuss your goals, and create a personalised treatment plan combining Julaine with complementary therapies for optimal results.
Contact Aestha Clinic today to schedule your comprehensive Julaine consultation and begin your journey toward naturally enhanced, long-lasting skin rejuvenation.
Julaine treatments are performed by licensed medical professionals. Individual results may vary. A thorough consultation is required to determine candidacy.
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Schedule Your Consultation Today
At our clinic, we understand that achieving natural-looking rejuvenation requires both advanced techniques and personalised treatment plans.
We take pride in offering this cutting-edge treatment as part of our commitment to providing effective, minimally invasive solutions that work with your body’s natural processes rather than against them.