Collagen Biostimulators
Lenisna vs Juvelook - The Future of Advanced Skin Rejuvenation
At Aestha Clinic, we’re constantly seeking out the most innovative collagen biostimulators that deliver real, lasting results for our clients. After years of working with traditional dermal fillers and seeing their limitations, we’ve been excited to witness the emergence of hybrid collagen biostimulators – treatments that don’t just mask ageing but actually reverse it at a cellular level.
Maximising collagen restoration with RF microneedling combination therapy
We’ve carefully sourced and introduced two exceptional collagen biostimulators that represent the cutting edge of regenerative aesthetics: Lenisna and Juvelook. These aren’t your typical skin boosters. Both harness the power of PDLLA (Poly-D,L-lactic acid) combined with hyaluronic acid to create what we consider the holy grail of skin rejuvenation – collagen biostimulators that provide immediate satisfaction whilst building long-term skin health. When we pair these advanced collagen biostimulators with our RF microneedling protocols, the results speak for themselves.

Understanding Hybrid Collagen Biostimulators
Unlike traditional dermal fillers that simply add volume, or basic skin boosters that only provide hydration, modern collagen biostimulators work on multiple levels:
- Immediate hydration and plumping through hyaluronic acid
- Long-term collagen stimulation via Poly-D,L-lactic acid (PDLLA)
- Structural skin improvement that continues for months post-treatment
Both Lenisna and Juvelook embody this innovative approach to collagen biostimulators, but with distinct characteristics that make each suitable for different treatment goals.
Lenisna: The Volume Powerhouse Among Collagen Biostimulators
What Makes Lenisna Unique
Lenisna is a hybrid collagen biostimulator consisting of 170mg of PDLLA and 30mg of hyaluronic acid, with spherical particles measuring 50-60 μm featuring a porous interior structure. This larger particle size and higher PDLLA concentration make it particularly effective among collagen biostimulators for:
Key Benefits:
- Deep wrinkle correction and nasolabial fold improvement
- Significant volume restoration in areas of substantial tissue loss
- Surgical scar treatment and morphological asymmetry correction
- Body contouring applications beyond facial rejuvenation
- Deep dermis to subdermal layer for structural support
Ideal Candidates for Lenisna:
- Patients with significant volume loss
- Those seeking treatment for deep static wrinkles
- Individuals requiring structural facial restoration
- Patients with surgical scars or significant skin depressions
Juvelook: The Glass Skin Specialist in Collagen Biostimulators
What Makes Juvelook Special
Juvelook contains 42.4mg of PDLLA and 7.5mg of non-cross-linked hyaluronic acid, specifically formulated for shallow dermal injections to achieve the coveted “glass skin” effect. Its ultrafine particle technology makes it uniquely suitable among collagen biostimulators for delicate areas.
Key Benefits:
- Pore refinement and skin texture improvement
- Under-eye area treatment (uniquely safe for periorbital use)
- Fine line prevention and correction
- Acne scar improvement with minimal risk of nodule formation
- Shallow dermal injections for surface enhancement
Ideal Candidates for Juvelook
- Younger patients seeking preventative treatments
- Those with mild to moderate skin concerns
- Patients wanting under-eye area improvement
- Individuals focusing on skin quality over volume restoration
Head-to-Head Comparison: Advanced Collagen Biostimulators
FEATURE | LENISNA | JUVELOOK |
---|---|---|
Primary Focus | Volume + Structure | Quality + Texture |
PDLLA Concentration | 170mg (High) | 42.4mg (Moderate) |
Particle Technology | Large spherical particles | Ultrafine patented particles |
Treatment Areas | Face, body, deep structures | Face, delicate areas, under-eyes |
Results Duration | 18-24 months | 6-18 months |
Downtime | Moderate (24-48 hours) | Minimal (1-3 days) |
Best For | Mature skin, volume loss | All ages, prevention, quality |


The RF Microneedling Synergy with Collagen Biostimulators
Why Combine RF Microneedling with Collagen Biostimulators?
RF microneedling devices such as Morpheus8 and Secret RF are best combined with collagen biostimulators for enhanced collagen stimulation. This combination creates what experts call the “sandwich effect”:
The Science Behind the Combination:
- RF microneedling creates controlled thermal injury in deeper skin layers
- Collagen biostimulators provide scaffolding and sustained collagen stimulation
- Synergistic healing results in superior collagen remodelling
- Reduced treatment frequency due to enhanced efficacy
Treatment Protocol Benefits
- Maximised collagen response from dual stimulation mechanisms
- Reduced overall downtime by combining treatments in single sessions
- Cost-effective approach with longer-lasting results
- Comprehensive skin remodelling addressing multiple concerns simultaneously
Treatment Protocols and Expectations for Collagen Biostimulators
Lenisna Protocol
Initial Series: 2-3 sessions spaced 6-8 weeks apart
Maintenance: Annual touch-ups
Combination: RF microneedling followed immediately by Lenisna injection
Results Timeline: Immediate volume, progressive improvement over 6 months
Juvelook Protocol
Initial Series: 3 sessions spaced 4 weeks apart
Maintenance: Every 12-18 months
Combination: Can be performed with RF microneedling in same session
Results Timeline: Immediate glow, continued improvement for 18 months

Expert Assessment: Personalised Collagen Biostimulator Selection
Professional Consultation is Key
Our expert medical professionals specialising in regenerative facial aesthetics understand that choosing the right collagen biostimulators requires individual assessment. During your comprehensive consultation, our specialists will:
Comprehensive Skin Analysis:
- Assess your specific skin quality, texture, and elasticity
- Evaluate intrinsic aging factors (genetics, natural collagen production)
- Consider extrinsic lifestyle factors (sun exposure, skincare routine, environmental stressors)
- Analyse facial anatomy and volume distribution patterns
Bespoke Treatment Protocol Development:
- Create customised collagen biostimulator treatment plans tailored to your unique concerns
- Determine optimal injection depths and techniques for your skin type
- Design combination therapy protocols incorporating RF microneedling timing
- Establish realistic timelines and maintenance schedules based on your lifestyle
Individualised Approach Factors:
- Age and skin maturity level
- Previous aesthetic treatments and responses
- Professional and social downtime availability
- Budget considerations and treatment frequency preferences
- Specific aesthetic goals and expectations
Making the Right Choice Among Collagen Biostimulators
While general guidelines exist, our medical professionals will advise which collagen biostimulator offers the most benefit for your specific situation:
Lenisna May Be Recommended If:
-
- Professional assessment reveals significant volume loss or deep wrinkles
- Your skin analysis indicates need for structural restoration
- You want maximum longevity (18-24 months) based on your lifestyle
- Treatment areas include body regions or surgical scars
- Your schedule accommodates fewer, more comprehensive maintenance sessions
Juvelook May Be Recommended If:
-
- Assessment focuses on skin quality enhancement and prevention
- You require treatment for delicate areas (particularly under-eyes)
- Your skin responds better to gradual, natural-looking improvements
- Professional evaluation suggests early preventative intervention
- Your aesthetic goals align with achieving the “glass skin” effect


Your Journey to Advanced Collagen Biostimulators Starts Here
While general guidelines exist, our medical professionals will advise which collagen biostimulator offers the most benefit for your specific situation:
Lenisna and Juvelook represent the pinnacle of collagen biostimulator technology, each excelling in different aspects of skin rejuvenation. When combined with RF microneedling, these advanced collagen biostimulators offer unprecedented results in collagen restoration and skin quality enhancement.
The Importance of Professional Expertise:
The key to success with collagen biostimulators lies in proper patient selection through professional assessment, expert administration by qualified medical professionals, and strategic combination with complementary technologies. Our specialists in regenerative facial aesthetics bring years of experience in evaluating individual skin needs and creating bespoke collagen biostimulator treatment protocols that account for both your aesthetic goals and lifestyle factors.
Your Journey to Optimal Results:
Every client receives a personalised approach based on comprehensive analysis of their skin quality, aging patterns, and individual circumstances. This ensures that whether you receive Lenisna for structural restoration or Juvelook for quality enhancement, your collagen biostimulator treatment plan is optimised for your unique needs.
As we move forward, these hybrid collagen biostimulators will continue to define the future of non-surgical aesthetic medicine, offering patients natural, long-lasting results that truly turn back the clock on ageing.
The bottom line: The combination of advanced collagen biostimulator technology with expert medical assessment creates the most sophisticated approach to facial rejuvenation available today. Our professional team ensures you receive not just cutting-edge collagen biostimulator treatment, but the right treatment for your individual needs and goals.
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At our clinic, we understand that achieving natural-looking rejuvenation requires both advanced techniques and personalised treatment plans.
We take pride in offering this cutting-edge treatment as part of our commitment to providing effective, minimally invasive solutions that work with your body’s natural processes rather than against them.